After a stroke, many individuals experience difficulty with ambulation, or walking. Some may not be able to ambulate independently, while others may be able to walk on their own but may have some difficulty keeping up their strength and endurance. There are many benefits of doing cyclocentric exercise at all stages of recovery after a stroke. Cyclocentric exercise may be used as a pre-ambulation re-training therapy or used in addition to an individual's walking program.

Some of the many benefits include:

• Improved cardiovascular functioning.
• Improved balance and stability.
• Individuals' weight bearing and limb loading are challenged.
• Assurance that equal work is done on both legs, without allowing for compensatory activity.
• Consecutive concentric and eccentric activation of the leg flexors and extensors.
• Enhanced proprioception (the knowledge of the position of the joint).
• Co-contraction of the muscles surrounding the knee which can decrease hyperextension of the knee while walking (a very common problem in stroke survivors).
• Enhanced kinematic pattern of walking before the individual actually ambulates.
• Improved ability to support oneself in stance phase during walking.
• Enhanced neurologic control.
• Increased ability to perform functional activities.
• Provision of a wider seat than most exercise bikes, which is a safety issue.