Duchenne muscular dystrophy (DMD) is a genetically X-linked disorder of skeletal muscle
characterized by progressive muscle atrophy. DMD is caused by various mutations in the DMD gene which result in a loss of the skeletal muscle protein dystrophin (Dys). One in 3500-6000 boys are affected with DMD, making DMD the most common of the human muscular dystrophies. Dys has been localized to the muscle cell plasmalemma by electron-microscopic immunoperoxidase techniques, and appears to be a cytoskeletal protein. The main function of Dys is the maintenance of mechanical stability at the muscle cell membrane so normal stresses encountered during contraction can be withstood without membrane disruption.
Disclaimer: Proper precautions must be taken before you begin an exercise program. An understanding of your current health status and potential problems is necessary for you to exercise safely. Please contact your physician if you have any concerns. This program is intended to incorporate high-intensity physical activity into your daily life, but should not be used in place of physical therapy, professional medical advice, or treatment.