NCHPAD Research Abstracts on Exercise for Persons with Multiple Sclerosis and Myasthenia Gravis
Petajan, J. H., & White, Andrea T. (1999). Recommendations for physical activity in patients with multiple sclerosis. Sports Medicine 27(3), 179-191.
It has been shown that individuals with multiple sclerosis (MS) can engage in aerobic exercise safely, and the result is increased fitness. Secondary benefits include reduced depression and anxiety as well as an improved sense of well-being. Improved fitness will decrease morbidity resulting from cardiovascular disease and other illnesses that develop as a consequence of immobility. This overview paper provides recommendations for physical activity for persons with MS.
Following a brief exercise history including ambulation, balance, coordination, and strength, a review of cardiopulmonary function and an electrocardiogram should be obtained, as well as a graded exercise test performed to estimate VO2max and Rating of Perceived Exertion (RPE). Then, an exercise prescription can be formulated according to the person's specific physical abilities and limitations. Regulation of body temperature must be monitored due to dysautonomia, a malfunction of the autonomic nervous system. Balance and coordination may also be enhanced with Swiss ball exercises and pool exercises.
Read the complete abstract at http://www.ncpad.org/125/1019/Recommendations~for~physical~activity~in~patients~with~
Stout, J. R., Eckerson, J. M., May, E., Coulter, C., & Bradley-Popovich, G. E. (2001). Effects of resistance exercise and creatine supplementation on myasthenia gravis: A case study. Medicine and Science in Sports and Exercise, 33(6), 869-872.
This article presents a case study that examines the effects of a 15-week resistance exercise program and creatine supplements on body composition, training volume, strength, and blood chemistry in a 26-year-old man with myasthenia gravis (MG). After a 15-week creatine supplementation and exercise program, the 26-year-old male showed a 6.8% increase in body weight, a 4.3% increase in fat-free mass, a 37.0% increase in upper-body strength, and a 15.0% increase in lower-body strength. The subject?s blood chemistry levels also stayed within normal limits for the entire 15-week study. The study demonstrates that resistance training in conjunction with creatine supplementation may lead to increases in strength and fat-free mass in those with myasthenia gravis.